The Biophysical Imaging Centre (BICEN)
The Biophysical Imaging Centre (BICEN) houses our super-resolution optical microscopy instrument development laboratories and our atomic force microscopy (AFM) instrument facility.
The basement laboratories in BICEN house our Atomic Force Microscopy (AFM) facility, which contains 5 high performance AFM systems from Bruker, JPK and Asylum Research. These include two fast scanning systems and two AFMs mounted on inverted optical microscopes. All of our systems are suitable for high resolution imaging and force measurement on biological samples and are situated in temperature controlled space which is suitable for working with category 2 pathogens. We also have three AFM instruments located in regular lab space, which are used for more general imaging. As well as using commercial instruments we also work on instrument development to improve spatial and temporal resolution, exploit novel contrast mechanisms and combine other microscopy techniques with AFM.
The optics laboratory is situated on the ground floor of the Hicks building in newly refurbished space. As with the AFM suite, the labs are temperature controlled and suitable for work with category 2 pathogens. Our aim is to develop and modify optical techniques in order to address specific biological problems. The techniques currently under development include: STORM, SIM, confocal, FLIM, FRET, light sheet, quantitative phase imaging and spectral STORM.
If you wish to collaborate or would like to use any of these microscopes, please contact Nic Mullin to discuss your requirements.